The crash happened in the 400 block of Mars Valencia Road in Adams Township, in Butler County, around 4:30 a.m. on Friday, August 26, reports WPXI.
Two garbage trucks collided and one plowed into a vacant former chiropractor's office, the outlet reports citing an unnamed local fire chief on the scene.
The garbage trucks are from two different companies, Waste Management, which is the one that crashed into the building, and a Vogel Disposal Service truck, reports WTAE.
The driver of the Waste Management vehicle was extracted and taken to an area hospital where he was pronounced deceased by a Butler County coroner, reports KDKA.
His exact cause and manner of death and his identity have yet to be released.
The roadway was closed near the intersection of Purvis Lane between Route 228 and Babcock Boulevard for five hours; impacting Mars and Pine Richland school districts' bus routes, WPXI reported.
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